Assaying for the effectiveness and efficiency of some local plant extracts in the control of dairy farm-associated bacteria pathogens using in vitro well diffusion technique

Though antimicrobial agents have been used for the effective control of infectious agents, there is a growing concern about emergence and re-emergence multidrug-resistant bacteria pathogens against commonly prescribed antibiotics. Consequently, gross reduction in effectiveness mechanism thereby increasing health care costs its associated consequences. Plant parts extracts crude forms local several ailments including those animals. Two-phase research was set-up. One, to isolate identify multi-drug from some small-scale farms Kwali, FCT, Abuja their drug resistance status. The second part screen evaluate effects common phytochemicals plants, viz; guava (Psidium guajava), ginger (Zingiber officinale), neem (Azadirachta indica), moringa (Moringa oleifera) previously isolated MDR (Salmonella spp. Clostridium sp. Staphylococcus aureus, Streptococcus E. coli.). aqueous, ethanolic methanolic plants were susceptibility test, minimum inhibitory concentration bactericidal concentrations using vitro agar disc diffusion protocol based on CLSI methods. results showed significant Inhibitory zones range 23-32mm. This agreement with done plant extracts. type solvent also influenced quality extract output. Based results, we concluded that activities comparable currently modern drugs tested. It justifiable therapeutic derived these would be emerging diseases contribute growth scientific knowledge herbal medicines as important alternatives or complementary treatment animal diseases. hereby recommended further (The third phase) carry out studies clinical efficacy trial, safety, toxicity affordability analyses well optimization upscaling parameters so proceed final step mass production tested products.